Paternal age explains a major portion of de novo germline mutation rate variability in healthy individuals

HIGHLIGHTS

  • who: Simon L. Girard and collaborators from the Neurological Institute, McGill University, Canada, Centre de Pharmacogénomique have published the research work: Paternal Age Explains a Major Portion of De Novo Germline Mutation Rate Variability in Healthy Individuals, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0164212]. October 10, 2016 of October/10,/2016
  • what: Using disease-free familial quartets the authors show that there is strong positive correlation between paternal age and germline DNM in healthy subjects. The authors show that rate of germline de novo single nucleotide variants (SNV) and indels . . .

     

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