Pathobiology of the klotho antiaging protein and therapeutic considerations

HIGHLIGHTS

  • who: FGF et al. from the Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, Department of Laboratory have published the research: Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations, in the Journal: (JOURNAL)

SUMMARY

    The expression level of these enzymes might be increased in various ways, for example through the action of insulin, growth factors and cytokines (Bzowska et_al, 2004; Chen CD, et_al, 2007; Maretzky et_al, 2008; Murphy, 2009). The renal physiological functions of Klotho have been extensively reviewed (Erben and Andrukhova, 2017; Kuro-o 2017; Zou et_al . . .

     

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