Pathogenesis and treatment of chronic rhinosinusitis from the perspective of sinonasal epithelial dysfunction

HIGHLIGHTS

  • who: Yuanqiong He from the University of Zurich, Switzerland have published the research: Pathogenesis and treatment of chronic rhinosinusitis from the perspective of sinonasal epithelial dysfunction, in the Journal: (JOURNAL)
  • what: The authors provide an elegant summary of the contributions of altered epithelial functions to the pathogenesis of CRS and discuss the possible influence of the current treatment regime on the sinonasal epithelium.

SUMMARY

    Interestingly, some studies have observed significantly decreased expression of ZO-1, occludin, claudin-1, JAM-1, DSG1, and DSG2 in the primary epithelial_cells of CRS patients as . . .

     

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