Pathogenesis of central nervous system germ cell tumors

HIGHLIGHTS

  • who: Siyuan Liu from the Osaka National Hospital (NHO), Japan The University of Tokyo, Japan have published the Article: Pathogenesis of central nervous system germ cell tumors, in the Journal: (JOURNAL)
  • what: IGCTs are clinically rare.

SUMMARY

    Histologically, IGCTs can be classified into eight types according to 2021 WHO guidelines, namely, mature teratoma, immature teratoma, teratoma with somatic-type malignancy, germinoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and mixed germ cell tumor (GCT). Chris Tan et_al concluded that IGCTs might be developed from neural stem_cells by upregulating the genes through OCT . . .

     

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