Pathogenic human variant that dislocates gata2 zinc fingers disrupts hematopoiesis gene expression and signaling networks mabel minji jung , siqi shen , giovanni a. botten , thomas olender , koichi r. katsumura ,

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  • who: Mabel from the Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, University of Chicago, Chicago, IL, USA have published the Article: Pathogenic Human Variant that Dislocates GATA2 Zinc Fingers Disrupts Hematopoiesis Gene Expression and Signaling Networks Mabel Minji Jung , Siqi Shen , Giovanni A. Botten , Thomas Olender , Koichi R. Katsumura ,, in the Journal: (JOURNAL)
  • how: Using the rescue assay the authors compared activities of GATA2 and 2 4 6 8 and 9aa variants to activate and repress transcription. qRT-PCR analysis with GATA2-expressing hi-77-/- cells confirmed Hdc Gata1 Il1rl1 . . .

     

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