Pathogenic mutation of tdp-43 impairs rna processing in a cell type-specific manner: implications for the pathogenesis of als/ftld

HIGHLIGHTS

• who: TDP- and collaborators from the IncAll other authors declare no competing financial interestsDepartment of Physiology, Keio University School of Medicine, Shinjuku, Tokyo, Japan have published the paper: Pathogenic Mutation of TDP-43 Impairs RNA Processing in a Cell Type-Specific Manner: Implications for the Pathogenesis of ALS/FTLD, in the Journal: (JOURNAL)
• what: This study characterizes global RNA processing impairments induced by mutant TDP-43 and reveals the unprecedented cell type specificity of TDP-43 LOF in ALS/FTLD pathogenesis. For the analysis of TDP-43 localization, TUBB3 staining was used to determine the . . .
  

   

  

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