Pathogenicity of misfolded and dimeric hla-b27 molecules

HIGHLIGHTS

  • who: Antony N. Antoniou et al. from the Division of Infection and Immunity/Centre of Rheumatology, Department of Immunology and Molecular Pathology, University College London, Windeyer Institute of Medical Science, Cleveland Street, London W T JF, UK have published the article: Pathogenicity of Misfolded and Dimeric HLA-B27 Molecules, in the Journal: (JOURNAL) of 28/01/2011
  • what: The authors discuss how these unusual biochemical structures may participate in cellular events leading to chronic inflammation and thus disease progression. This latter idea is referred to as the "misfolding hypothesis" and is the main focus of . . .

     

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