Pathomorphological diagnostic criteria for focal cortical dysplasias and other common epileptogenic lesions—review of the literature

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SUMMARY

    The brief history of FCD marked its origin back in 1971 when Taylor et_al reported a case series of 10 patients with pharmacoresistant epilepsy, in whose resected brain specimens they found cortical dyslamination, large neurones with bizarre morphology, and ballooned cells. In 2004, Palmini et_al put forward recommendations for FCD classification, namely: specific terminology related to the different types of changed cells found in the brain parenchyma of FCD patients; new descriptive terms defining the lesions formerly comprising "microdysgenesis", which as a term itself is no longer used; in-depth classification of histopathological characteristics . . .

     

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