Patient derived organoids confirm that pi3k/akt signalling is an escape pathway for radioresistance and a target for therapy in rectal cancer

HIGHLIGHTS

  • who: Kasun Wanigasooriya from the Institute of Cancer and Genomic Science, College of Medical and Dental Science, University of Birmingham, Birmingham, Birmingham, United Kingdom have published the paper: Patient Derived Organoids Confirm That PI3K/AKT Signalling Is an Escape Pathway for Radioresistance and a Target for Therapy in Rectal Cancer, in the Journal: (JOURNAL)
  • what: After evaluating PDOs response to radiation, the authors aimed to identify novel genes and pathways that promote radiation resistance by comparing the pre-treatment transcriptomes of radiation-sensitive and radiation-resistant PDOs.
  • how: The authors chose to include . . .

     

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