Patient-derived xenograft (pdx) models, applications and challenges in cancer research

HIGHLIGHTS

  • who: Shahrokh Abdolahi from the (UNIVERSITY) have published the research: Patient-derived xenograft (PDX) models, applications and challenges in cancer research, in the Journal: (JOURNAL)
  • what: These data suggest that conventional preclinical models such as monolayer cell lines culture or syngeneic and xenograft models are the main reason for the failure of most anti-cancer agents in humans . The overall goal of NCI is to establish a long-term storage site for at least 1000 PDX models so that researchers have sufficient biological and clinical diversity to conduct their studies . Cancer biology This model has . . .

     

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