Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system

HIGHLIGHTS

• who: Sebastian Schuth from the Tumor tissue biopsies were obtained from surgically resected tumor specimens from patients who underwent primary resection at the Department of General, Visceral and Transplantation Surgery, Heidelberg University HospitalThe study was approved by the ethical committee of University of Heidelberg (ethic votes, , /2011, /, and, /2021) and was conducted in accordance with the Helsinki Declaration. All patients provided written informed consent prior to acquisition of tissue. Tumor entity was confirmed by pathological assessment of the resected specimens. Establishment and culture of PDAC tumor organoids have published the article: Patient-specific modeling of stroma-mediated . . .
  

   

  

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