Patients deriving long-term benefit from immune checkpoint inhibitors demonstrate conserved patterns of site-specific mutations

HIGHLIGHTS

  • who: Daniel R. Principe from the University of have published the paper: Patients deriving long-term benefit from immune checkpoint inhibitors demonstrate conserved patterns of site-specific mutations, in the Journal: Scientific Reports Scientific Reports
  • what: The authors evaluated genomic data from a large pan-cancer cohort initially used to support the predictive value of TMB in patients receiving ICI-based immunotherapy.
  • how: Categorical data were evaluated using the Pearson's chi-squared test. For time-to-endpoint/survival analyses data were analyzed using the Kaplan Meier method/log rank test with hazard . . .

     

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