Pax6 mutant cerebral organoids partially recapitulate phenotypes of pax6 mutant mouse strains

HIGHLIGHTS

  • who: Nurfarhana Ferdaos et al. from the Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom, Department have published the research: Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains, in the Journal: PLOS ONE of July/22,/2022
  • future: In future studies single cell RNA seq will provide more information about the regional identities of cells in the organoids and may highlight any differences in gene_expression that could account for the different effect of Pax6 loss on progenitor proliferation.

SUMMARY

    Embryonic development of the mammalian . . .

     

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