Pcsk9- d374y suppresses hepatocyte migration through downregulating free cholesterol efflux rate and activity of extracellular signal-regulated kinase

HIGHLIGHTS

  • who: Lei Huang and colleagues from the of MARA, Agricultural Genomics Institute at, Chinese Academy of Agricultural Sciences, China have published the paper: PCSK9- D374Y Suppresses Hepatocyte Migration through Downregulating Free Cholesterol Efflux Rate and Activity of Extracellular Signal-Regulated Kinase, in the Journal: Analytical Cellular Pathology 0 of 14/01/2022
  • what: The authors evaluate its effects in the human hepatoma carcinoma cell line HepG2 including proliferation migration and free cholesterol transport. The authors demonstrate that PCSK9 overexpression significantly inhibits the horizontal motion and vertical migration of HepG2 cells.
  • how: The experimental . . .

     

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