Pd-l1 inhibits t cell-induced cytokines and hyaluronan expression via the cd40-cd40l pathway in orbital fibroblasts from patients with thyroid associated ophthalmopathy

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  • who: Zhibin Liu and colleagues from the Technion Institute of Miltenyi Biotec, United States Auburn University, United States have published the research work: PD-L1 Inhibits T Cell-Induced Cytokines and Hyaluronan Expression via the CD40-CD40L Pathway in Orbital Fibroblasts From Patients With Thyroid Associated Ophthalmopathy, in the Journal: (JOURNAL)
  • what: The authors determine that TAO-OFs do not express PD-L1, and exogenous PD-L1 attenuates CD40-CD40L-mediated T_cells activating TAOOFs by inhibiting T_cell function, thus inhibiting immune Frontiers in Immunology | www.frontiersin.org May 2022 | Volume 13 | Article 849480 PD-L1 . . .

     

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