Pdgfrβ+ cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

HIGHLIGHTS

• who: Diana Sá da Bandeira from the Medical Research Institute University of Edinburgh, TJ Edinburgh, UK have published the research work: PDGFRβ+ cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny, in the Journal: (JOURNAL) of July/19,/2022
• what: The authors show is expressed distinct perivascular stromal cell layers surrounding the mid-gestation dorsal aorta and its deletion impairs hematopoiesis. The authors demonstrate PDGFRb+ cells play a dual role murine hematopoiesis. The aim of this study was to identify and characterize the perivascular cells that constitute the HSPC microenvironment . . .
  

   

  

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