Pdhb-as suppresses cervical cancer progression and cisplatin resistance via inhibition on wnt/β-catenin pathway

HIGHLIGHTS

• who: Chi Chi from the In vivo assay Five-six-week-old nude mice purchased from Beijing Vital River Laboratory Animal Technology Co [, ]Ltd. (China) were used for xenograft models. HeLa cells transfected with pcDNA3.1, pcDNA3.1-PDHB-AS, and HKF were stably separated with trypsin and washed twice with sterilized PBS. Then , u00d7 , cells in, ., ml PBS were subcutaneously inoculated in the flanks of the mice. Tumor growth was monitored every , days after being apparently observed and the tumor size was detected using calipers. Four weeks after inoculation, the mice were sacrificed. Animal research was . . .
  

   

  

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