HIGHLIGHTS
- who: Duk-Shin Lee and Ji-Eun Kim from the Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym have published the research: PDI-Mediated Reduction of Disulfide Bond on PSD95 Increases Spontaneous Seizure Activity by Regulating NR2A-PSD95 Interaction in Epileptic Rats Independent of S-Nitrosylation, in the Journal: (JOURNAL)
- what: The authors demonstrate that PILO-induced acute seizure activity significantly increased the bindings of PDI to NR2A, but not to PSD95, while it decreased the NR2A-PSD95. In the present study, acute seizures and spontaneous seizures in epileptic rats . . .
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