Pediatric-type high-grade neuroepithelial tumors with cic gene fusion share a common dna methylation signature

HIGHLIGHTS

  • who: Philipp Sievers from the Published in partnership with The Hormel Institute, University of Minnesota have published the research: Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature, in the Journal: (JOURNAL)

SUMMARY

    Pediatric neoplasms in the central nervous system (CNS) are extremely heterogeneous and diagnostically challenging tumors. According to data from the Central Brain Tumor Registry of the United_States (CBTRUS), CNS tumors have become the leading cause of cancer-related death in childhood1. DNA methylation profiling of CNS tumors has been demonstrated to be a . . .

     

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