Peg spacer length substantially affects antibody-based nanocarrier targeting of dendritic cell subsets

HIGHLIGHTS

  • who: Maximilian Brückner et al. from the Department of Dermatology, University Medical Center of the Johannes Gutenberg University Mainz have published the Article: PEG Spacer Length Substantially Affects Antibody-Based Nanocarrier Targeting of Dendritic Cell Subsets, in the Journal: Pharmaceutics 2022, 1614 of /2022/
  • what: The authors demonstrate cell type-specific targeting for dendritic cells (DC) as cellular key regulators of immune responses. The authors focused on the surface modification of nanocarriers with different molecular weight linkers (0.65 2 and 5 kDa) and their ability to reduce undesired cell uptake while achieving efficient . . .

     

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