Pegylation in pharmaceutical development: current status and emerging trends in macromolecular and immunotherapeutic drugs

HIGHLIGHTS

  • Who: Karthick R. Santhanakrishnan et al. from the (UNIVERSITY) have published the Article: Received 07/10/2024 Review began 07/25/2024 Review ended 08/07/2024 Published 08/12/2024, in the Journal: (JOURNAL) of August/12,/2024

SUMMARY

    And Background Attaching polyethylene glycol (PEG) to nano lipid drug carriers prolongs their circulation time in the bloodstream by preventing recognition and removal by the immune system, particularly monocytes and macrophages. The PEG coating masks the carriers from opsonins, proteins that tag foreign particles for clearance by phagocytic cells, thereby allowing the drug . . .

     

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