Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis

HIGHLIGHTS

  • who: Ni Yang from the Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, China have published the research work: Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis, in the Journal: (JOURNAL)
  • what: The authors develop a biomimetic ApoA-I mimetic peptide-modified membrane-wrapped F127 polymer and chemokine receptors on neutrophils the membrane coating can endow the nanocarrier with synovitis-targeting ability with subsequent recruitment to the synovial fluid under the chemotactic effects of IL-8.
  • how: All animal studies were conducted in . . .

     

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