Peptide targeting the interaction of s protein cysteine-rich domain with ezrin restricts pan-coronavirus infection

HIGHLIGHTS

• who: Zhuanchang Wu from the (UNIVERSITY) have published the article: Peptide targeting the interaction of S protein cysteine-rich domain with Ezrin restricts pan-coronavirus infection, in the Journal: (JOURNAL) of 24/07/2022
• what: Taken together, the study provides a novel strategy targeting CRD domain with peptide to efficiently against broad-spectrum HCoVs infection.

SUMMARY

Received S-CRD peptide as an effective approach to inhibit cell fusion and viral infectivity of multiple HCoVs. To assess the inhibitory activity of S-CRD peptide against authentic coronavirus infection, HCoV-229E and SARS . . .

 



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