Perfluorocarbon nanodroplets as potential nanocarriers for brain delivery assisted by focused ultrasound-mediated blood-brain barrier disruption

HIGHLIGHTS

  • who: Charlotte Bu00e9rard and collaborators from the Universitu00e9 Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Service Hospitalier Fru00e9du00e9ric Joliot have published the research work: Perfluorocarbon Nanodroplets as Potential Nanocarriers for Brain Delivery Assisted by Focused Ultrasound-Mediated Blood-Brain Barrier Disruption, in the Journal: Pharmaceutics 2022, 14, 1498. of /2022/
  • what: In this work a stable freeze-dried emulsion of perfluorooctyl bromide nanodroplets stabilized with home-made fluorinated surfactants able to carry hydrophobic agents is developed. The authors demonstrate that the nanodroplets developed in this work are biocompatible and appear to be promising NCs, capable of . . .

     

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