Performance evaluation of newly developed surrogate virus neutralization tests for detecting neutralizing antibodies against sars-cov-2

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SUMMARY

    The receiver operating char- acteristics (ROC) curve analysis to determine the cut-off for eCoV-CN and rCoV-RN are illustrated in Fig 1. For rCoV-RN, ROC curve analysis revealed that ≥ 0.83 of the P ratio (signal value ratio generated from the rCoV-RN, details are described below "Methods" section below) was the best cut-off for the positive for NAbs. Both assays showed statistically significant positive or negative Spearman`s rho (r) values to the P ­ RNT50 (0.668 for eCoV-CN and - 0.694 for rCoV-RN, both P and . . .

     

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