Pericyte derived chemokines amplify neutrophil recruitment across the cerebrovascular endothelial barrier

HIGHLIGHTS

• who: Eliza Gil from the Université Toulouse III, France University of Würzburg, Germany have published the research work: Pericyte derived chemokines amplify neutrophil recruitment across the cerebrovascular endothelial barrier, in the Journal: (JOURNAL)
• what: The authors show the addition of HBVP significantly enhanced neutrophil transmigration across the endothelial barrier in response to inflammatory cues, interestingly without compromising small_molecule barrier integrity. Whether Spn and other bacterial causes of pyogenic meningitis can migrate across the endothelial barrier to stimulate perivascular macrophages was not the focus of the study . The experiments were limited to Spn infection, but . . .
  

   

  

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