HIGHLIGHTS
- who: Chun-yang Huang from the DepartmentUniversity, Taipei, Taiwan, have published the article: PERM1 regulates genes involved in fatty acid metabolism in the heart by interacting with PPARu03b1 and PGC-1u03b1, in the Journal: Scientific Reports Scientific Reports
SUMMARY
Previous investigations primarily conducted with in_vitro cell cultures have shown that PERM1 is expressed in skeletal and cardiac muscles and involved in the expression of genes regulating metabolism1,2. Unbiased bioinformatic analyses of the Perm1 KO hearts and validation with biochemical assays suggest that endogenous PERM1 in the heart mediates expression of genes involved . . .
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