Peroxisomal defects in microglial cells induce a disease-associated microglial signature

HIGHLIGHTS

• who: ufeffQuentinufeff ufeffRaasufeff from the Federal of Rio Grande do Norte, Brazil have published the research: Peroxisomal defects in microglial cells induce a disease-associated microglial signature, in the Journal: (JOURNAL)
• what: The authors focused on 5 upregulated genes of the DAM list which encode secreted proteins: Cathepsin b (Ctsb), Osteactivin (Gpnmb), constitutes the largest group of DEGs, individual mutants have demonstrated specificity and, in some cases, contradictory results. Although many signaling pathways, cell division and cell cycle features, phagocytosis, and immune_response of microglial BV-2 mutant cells appear to be largely affected, the authors . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.