Peroxisome proliferator-activated receptor γ down-regulates follistatin in intestinal epithelial cells through sp1*

HIGHLIGHTS

• who: Brian M. Necela from the (UNIVERSITY) have published the paper: Peroxisome Proliferator-activated Receptor γ Down-regulates Follistatin in Intestinal Epithelial Cells through SP1*, in the Journal: (JOURNAL) of October/31,/2008
• what: Using RIE-1 cells, the authors show that activation of PPAR␥ by rosiglitazone reduced follistatin mRNA levels in a dose- and concentration-dependent manner. The authors report that follistatin is differentially expressed in epithelial crypts of the small and large intestine and through the use of a non-transformed, rat intestinal cell line (RIE-1) the authors illustrate that intestinal cells express . . .
  

   

  

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