Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal ca1 synapses requires n-cadherin

HIGHLIGHTS

• who: Synapses Requires N-Cadherin et al. from the Friedman Brain Institute Jefferson University have published the Article: Persistence of Coordinated Long-Term Potentiation and Dendritic Spine Enlargement at Mature Hippocampal CA1 Synapses Requires N-Cadherin, in the Journal: (JOURNAL) of July/28,/2010
• what: The authors investigate the adhesion molecule N-cadherin as a prime candidate for coordinating synaptic structural and functional plasticity. Using a genetic approach, the authors show that in the absence of N-cadherin, neither LTP nor spine enlargement persist in adult hippocampus, while N-cadherin is dispensable for LTD. The . . .
  

   

  

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