Personalized in vitro extracellular matrix models of collagen vi-related muscular dystrophies

HIGHLIGHTS

  • who: Muscular Dystrophies and collaborators from the University of Pittsburgh, United States have published the research work: Personalized in vitro Extracellular Matrix Models of Collagen VI-Related Muscular Dystrophies, in the Journal: (JOURNAL)
  • what: The authors focused on elastic fibers given their involvement in disease pathogenesis and cell-ECM regulation (Paco et_al, 2015), (Thakkar et_al, 2014). The authors obtained CDMs from COL6-RD patients and controls to characterize differences in their composition and architecture, partially depending on the severity of the phenotype. This study has been performed according to current legislation on Biomedical Investigation in . . .

     

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