Perspective: structure determination of protein-ligand complexes at room temperature using x-ray diffraction approaches

HIGHLIGHTS

• who: January and collaborators from the Jawaharlal Nehru University, India have published the research work: Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches, in the Journal: (JOURNAL)
• what: This approach has the potential for much faster reaction initiation as diffusion into the crystal is not a significant factor, due to pre-soaking with the photocage.

SUMMARY

The first dedicated beamline to do this was the versatile macromolecular crystallography in situ (VMXi) beamline at Diamond Light Source (Sanchez-Weatherby et_al, 2019), with several additional instruments . . .

 



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