Perturbation of critical prolines in gloeobacter violaceus ligand-gated ion channel (glic) supports conserved gating motions among cys-loop receptors*

HIGHLIGHTS

• who: Matthew Rienzo from the (UNIVERSITY) have published the Article: Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors*, in the Journal: (JOURNAL) of March/18,/2016
• what: The authors show that the gating energetics for GLIC appear to depend significantly on the structure of the YPF motif of the Cys-loop, similar to what has previously been seen in eukaryotic nAChRs .
• future: Studies will be required to delineate the structural consequences of mutations at this position and may illuminate poorly understood . . .
  

   

  

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