Perturbed fatty-acid metabolism is linked to localized chromatin hyperacetylation, increased stress-response gene expression and resistance to oxidative stress

HIGHLIGHTS

  • who: Jarmila Princovu00e1 and colleagues from the Editor:, University College Dublin, Environment, University College London, London, United Kingdom have published the Article: Perturbed fatty-acid metabolism is linked to localized chromatin hyperacetylation, increased stress-response gene expression and resistance to oxidative stress, in the Journal: (JOURNAL) of January/10,/2023
  • what: The authors report that fission yeast cells defective in fatty acid synthesis (cbf11 mga2 and ACC/cut6 mutants; FAS inhibition) show increased expression of a subset of stress-response genes. The authors propose that changes in lipid metabolism can regulate the chromatin and transcription . . .

     

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