Pgc-14 interacts with rest to upregulate neuronal genes and augment energy consumption in developing cardiomyocytes

HIGHLIGHTS

  • who: Tomi Tuomainen et al. from the AIVirtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland have published the research: PGC-14 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes, in the Journal: Cells 2022, 11, 2944. of /2022/
  • what: The authors assessed cardiac PGC-1u03b1 expression and detected Pgc-1u03b14 as the main non-canonical isoform expressed in the heart.

SUMMARY

    In cardiac myocytes, as in other metabolically active cells, peroxisome proliferatoractivated receptor (PPAR) gamma coactivator 1-alpha (PGC-1α) is an . . .

     

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