Pgrmc1 regulates cellular senescence via modulating foxo1 expression in decidualizing endometrial stromal cells

HIGHLIGHTS

  • who: Atsuya Tsuru and colleagues from the Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences have published the article: PGRMC1 Regulates Cellular Senescence via Modulating FOXO1 Expression in Decidualizing Endometrial Stromal Cells, in the Journal: Biomolecules 2022, 12, x FOR PEER REVIEW of /2022/
  • what: This study investigated the role of PGRMC1 in cellular senescence accompanying decidualization.
  • how: The authors showed that the small interfering RNA (siRNA)-mediated knockdown of and the inhibition of by AG-205 increased the expression of the transcription factor forkhead box protein O1 (FOXO1) and . . .

     

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