Phagocytosis of plasmodium falciparum ring-stage parasites predicts protection against malaria

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  • who: Fauzia K. Musasia from the Heidelberg University of Biotechnology, Hochschule Rhein-Waal, Kleve, Germany have published the Article: Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Antibodies targeting rIEs were shown to mediate opsonic phagocytosis but the impact of this activity has neither been analysed in gold standard prospective cohort studies, nor investigated in contemporary human malaria challenge studies. The authors demonstrate that antibody-dependent phagocytosis of rIEs and uninfected erythrocytes (uEs) from ring cultures was strongly correlated with protection. The authors show . . .

     

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