HIGHLIGHTS
- who: Andrey P. Babenko from the (UNIVERSITY) have published the research work: Pharmaco-topology of Sulfonylurea Receptors, in the Journal: (JOURNAL)
SUMMARY
The human SUR1, SUR2A, and KIR6.2 cDNAs have been described previously, as have the cDNAs encoding chimeric SUR I through VI, IX through XIV, and XVII (see Fig 1, left panel). The free Mg2⫹ concentration in all Mg2⫹-containing internal solutions was maintained at a quasi-cytosolic level of ⬃0.7 mM, as described previously. Comparison of the stimulation of chimeric SUR/KIR6.2 channels by diazoxide and cromakalim demonstrated . . .
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