HIGHLIGHTS
- who: Yoonhee Nam from the (UNIVERSITY) have published the research: Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma, in the Journal: (JOURNAL)
- what: While previous studies utilized a small subset of conventional cancer cell lines to identify TMZ-resistant features , the authors propose to investigate patient-derived GSCs, which might indicate treatment outcomes and reveal clinical-relevant mechanisms of drug resistance. The authors aimed to collect molecular profiles of the GSCs and develop a classification model to predict TMZ sensitivity to improve patient management. To facilitate the use of . . .
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