Pharmacogenomics implementation in cardiovascular disease in a highly diverse population: initial findings and lessons learned from a pilot study in united arab emirates

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SUMMARY

    Indeed, translating PGx findings into clinical recommendations, like genetic-based dose adjustments or suggesting alternative medications, facilitates adoption by practitioners. Warfarin genetic dosing utilizes PGx-algorithms built on genetic testing results and clinical factors to suggest a starting dose of warfarin within 20% of the actual maintenance dose. At the global level, PGx studies in ethnically diverse populations are believed to increase the power of genetic discovery, strengthen the relevance of PGx-implementation in the clinic, and ensure the generalizability of findings. Although the current study is not designed to test similar findings, as . . .

     

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