Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome

HIGHLIGHTS

  • who: Xiaofeng Wang from the (UNIVERSITY) have published the research: Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome, in the Journal: (JOURNAL)
  • what: The aim of this population pharmacokinetics (PK) analysis was to characterize the PK of terlipressin and its active metabolite lysine-vasopressin (L-VP) in patients with hepatorenal syndrome (HRS) following intravenous administration of terlipressin 1 mg to 2 mg every 6 h. Using the PK and PD data from two clinical studies in patients with HRS, the objectives of this analysis were to characterize the PK and PD, as . . .

     

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