Pharmacokinetic variability drives palbociclib-induced neutropenia in metastatic breast cancer patients: drug-drug interactions are the usual suspects

HIGHLIGHTS

  • who: Fanny Leenhardt et al. from the Institut du Cancer de Montpellier, Universitu00e9 de Montpellier, rue des Apothicaires, Montpellier, France have published the Article: Pharmacokinetic Variability Drives Palbociclib-Induced Neutropenia in Metastatic Breast Cancer Patients: Drug-Drug Interactions Are the Usual Suspects, in the Journal: Pharmaceutics 2022, 14, 841. of 18/06/2018
  • what: The pharmacokinetic-toxicity relationship and PK variability of palbociclib were characterized in real-life metastatic breast cancer patients (n=62).

SUMMARY

    Neutropenia is one of the most frequently reported toxicities when using oncologic drugs. Of 12 Although . . .

     

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