Pharmacokinetics of fl uorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (np751), a novel anticancer antagonist

HIGHLIGHTS

  • who: NP and colleagues from the National Institute of Pharmaceutical Education and Research, India Roma Tre University, Italy have published the Article: Pharmacokinetics of fl uorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (NP751), a novel anticancer antagonist, in the Journal: (JOURNAL)
  • what: The aim of this study was to develop a quantitative LCMS/MS method for fb-PMT and to evaluate the PK parameters of fb-PMT, such as peak plasma concentration (Cmax) and area under the curve (AUC), in mice, rats and monkeys.
  • future: Biodistribution and elimination kinetics will be determined in future . . .

     

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