HIGHLIGHTS
- who: Author(s et al. from the Dept, University Gothenburg have published the paper: Pharmacokinetics of Intravenously (DIZ101), Subcutaneously (DIZ102), and Intestinally (LCIG) Infused Levodopa in Advanced Parkinson Disease, in the Journal: (JOURNAL)
- what: The aims this trial were to investigate if continuous subcutaneous or intravenous infusion with a continuously buffered acidic levodopa/carbidopa solution yields steady state plasma concentrations levodopa that are equivalent in magnitude and non-inferior in variability to those obtained with LCIG in patients with advanced Parkinson`s disease. This analysis showed the bioavailability of levodopa to be 80% with LCIG . . .
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