Pharmacokinetics of tamoxifen and its major metabolites and the effect of the african ancestry specific cyp2d6*17 variant on the formation of the active metabolite, endoxifen

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• who: Comfort Ropafadzo Kanji et al. from the African Institute of Biomedical Science and Technology (AIBST), Harare POBox, Zimbabwe Department of Clinical Pharmacology, University of Zimbabwe College of Health Sciences, Johannesburg, South Africa have published the Article: Pharmacokinetics of Tamoxifen and Its Major Metabolites and the Effect of the African Ancestry Specific CYP2D6*17 Variant on the Formation of the Active Metabolite, Endoxifen, in the Journal: (JOURNAL)
• what: The authors aimed to investigate the effects of an African-specific CYP2D6 variant allele CYP2D6 17 on the pharmacokinetics (PK) of TAM and its active metabolites in . . .
  

   

  

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