Pharmacological activation of piezo1 in human red blood cells prevents plasmodium falciparum invasion

HIGHLIGHTS

  • who: Rakhee Lohia from the University Montpellier, CNRS UMR5294, Montpellier, France have published the Article: Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion, in the Journal: (JOURNAL)
  • what: The authors demonstrate in vitro that human red blood cell (RBC) infection by Plasmodium falciparum is prevented by the pharmacological activation PIEZO1. In this study, taking advantage of an in_vitro model of human RBC infection by P. falciparum, the authors aimed at exploring the antimalarial activity of PIEZO1 pharmacological activators and at determining which step of the infection cycle is PIEZO1 sensitive . . .

     

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