Pharmacological correction of excitation/inhibition imbalance in down syndrome mouse models

HIGHLIGHTS

• who: Jean M. Delabar from the Université Diderot, Cité, Adaptive Functional Biology, Centre National, Illkirch, France, Key-Obs, Orléans, France Johns Hopkins University, USA have published the article: Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models, in the Journal: (JOURNAL)
• what: The authors investigated the molecular effects of a commercial green tea extract, POL60, on murine mBACtgDyrk1a and Ts65Dn models, at a dose similar to the one used in the prior report. The authors report the phenotypic rescues observed in adult murine models of DS after a 1-month oral treatment . . .
  

   

  

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