Pharmacological inhibition of lipid import and transport proteins in ovarian cancer

HIGHLIGHTS

  • who: Lisa Lemberger and colleagues from the University of Vienna, Vienna, Austria have published the Article: Pharmacological Inhibition of Lipid Import and Transport Proteins in Ovarian Cancer, in the Journal: Cancers 2022, 6004 of /2022/
  • what: The authors show that exposure of OC cell cultures to small_molecule inhibitors of these lipid handling proteins caused drug-specific, dose-/time-dependent inhibition of FA and LDL uptake. The authors investigated whether proteins that facilitate the uptake of FA and lipids from the tissue microenvironment into the OC cells and mediate their subsequent intracellular transport could represent additional . . .

     

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