Pharmacological inhibition of pkcθ counteracts muscle disease in a mouse model of duchenne muscular dystrophy

HIGHLIGHTS

• who: Muscular dystrophy and collaborators from the Deptof Anatomy, Histology, Forensic Medicine and Orthopedics, Unit of Histology and MedEmbryology, CE-BEMM and Interuniversity Institute of Myology, Sapienza University of Rome, Rome, Italy have published the article: Pharmacological Inhibition of PKCu03b8 Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy, in the Journal: (JOURNAL)
• what: The authors show that treatment led to a significant reduction in damage associated with reduced immune cells infiltration reduced inflammatory pathways activation and maintained regeneration. The authors show that in_vivo pharmacological inhibition of PKCu03b8 in mdx mice significantly ameliorates . . .
  

   

  

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