HIGHLIGHTS
- who: Baihai Jiao from the Division of Nephrology, Department of Medicine, University of Connecticut School of Medicine, Farmington, CT, United States have published the research work: Pharmacological Inhibition of STAT6 Ameliorates Myeloid Fibroblast Activation and Alternative Macrophage Polarization in Renal Fibrosis, in the Journal: (JOURNAL)
- what: The authors evaluated the potential therapeutic role of AS1517499, a potent and selective STAT6 inhibitor , in myeloid fibroblast activation and development of renal fibrosis in two experimental murine models. The authors show that treatment with AS1517499 inhibits the number of CD206 and PDGFR-b dual positive cells in the . . .
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